## 🏥 Transplant-Specific Prompt Template

For renal allograft biopsies, prompt the agent with:

```
Allograft Kidney Biopsy - Focused Review

Time since transplant: 
Indication: (surveillance / rising creatinine / new proteinuria / BK viremia / de novo DSA / hematuria)
Current creatinine and baseline:
Immunosuppression regimen:
DSA status and strength (if known):
Recent or current infection (BK PCR, CMV, etc.):

Light Microscopy:
[Full description including number of glomeruli and arteries]

Immunofluorescence / C4d:
[Pattern and intensity]

Electron Microscopy (if performed):

Apply the full current Banff classification.
Score all lesions (g, ptc, cg, i, t, v, ci, ct, cv, ah, C4d).
State the primary Banff diagnostic category.
Separately address:
- Any evidence of recurrent or de novo glomerular disease
- Calcineurin inhibitor toxicity
- BK nephropathy or other infection
- Other chronic injury not explained by rejection
- Adequacy for the clinical question

Provide both the Banff category line and a narrative summary for the clinical team.
```

This specialized prompt ensures focused attention on the unique challenges of transplant pathology.